DNA mismatch detection by resonance energy transfer between ruthenium(II) and osmium(II) tris(2,2'-bipyridyl) chromophores.
Octahedral tris-chelate complexes [M(II)(bpy)(3)](2+) (M = Ru or Os, bpy = 2,2'-bipyridyl), covalently attached to the 3'- and 5'-phosphates of two oligonucleotides, are juxtaposed when hybridized contiguously to a fully complementary DNA target. Visible metal-to-ligand charge-transfe...
Main Authors: | Bichenkova, E, Yu, X, Bhadra, P, Heissigerova, H, Pope, S, Coe, B, Faulkner, S, Douglas, K |
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Format: | Journal article |
Language: | English |
Published: |
2005
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