Unicameral bone cysts: review of etiopathogenesis and current concepts in diagnosis and management

Objective This article aims to review the epidemiology, etio-pathogenesis and updates in clinical diagnostics and management of unicameral bone cysts (UBC). Methods A computerized literature search using Cochrane database of systematic reviews, EMBASE and PubMed was performed. MeSH (Medical Subject...

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Päätekijät: Rajasekaran, RB, Krishnamoorthy, V, Gulia, A
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: Springer 2022
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author Rajasekaran, RB
Krishnamoorthy, V
Gulia, A
author_facet Rajasekaran, RB
Krishnamoorthy, V
Gulia, A
author_sort Rajasekaran, RB
collection OXFORD
description Objective This article aims to review the epidemiology, etio-pathogenesis and updates in clinical diagnostics and management of unicameral bone cysts (UBC). Methods A computerized literature search using Cochrane database of systematic reviews, EMBASE and PubMed was performed. MeSH (Medical Subject Headings) terms used in searches included the following sub-headings: “unicameral bone cyst”, “epidemiology”, “etiology”, “pathogenesis”, “diagnosis”, “management” and “surgery”. Studies were analyzed based on clinical relevance for the practicing orthopedic surgeon. Results UBC accounts for 3% of all bone tumors and is asymptomatic in most cases. Nearly 85% of cases occur in children and adolescents, with more than 90% involving the proximal humerus and proximal femur. Despite multiple theories proposed, the exact etiology is still unclear. Diagnosis is straightforward, with radiographs and MRI aiding in it. While non-surgical treatment is recommended in most cases, in those warranting surgery, combined minimal-invasive techniques involving decompression of cyst and stabilization have gained importance in recent times. Conclusion There is variation in the diagnosis and treatment of UBCs among surgeons. Due to the vast heterogeneity of reported studies, no one method is the ideal standard of care. As most UBCs tend to resolve by skeletal maturity, clinicians need to balance the likelihood of successful treatment with morbidity associated with procedures and the risks of developing a pathological fracture. Study Design Review Article.
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spelling oxford-uuid:15ca1232-65f6-4d4f-abbf-e4e22c59f8382022-06-28T08:03:02ZUnicameral bone cysts: review of etiopathogenesis and current concepts in diagnosis and managementJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:15ca1232-65f6-4d4f-abbf-e4e22c59f838EnglishSymplectic ElementsSpringer2022Rajasekaran, RBKrishnamoorthy, VGulia, AObjective This article aims to review the epidemiology, etio-pathogenesis and updates in clinical diagnostics and management of unicameral bone cysts (UBC). Methods A computerized literature search using Cochrane database of systematic reviews, EMBASE and PubMed was performed. MeSH (Medical Subject Headings) terms used in searches included the following sub-headings: “unicameral bone cyst”, “epidemiology”, “etiology”, “pathogenesis”, “diagnosis”, “management” and “surgery”. Studies were analyzed based on clinical relevance for the practicing orthopedic surgeon. Results UBC accounts for 3% of all bone tumors and is asymptomatic in most cases. Nearly 85% of cases occur in children and adolescents, with more than 90% involving the proximal humerus and proximal femur. Despite multiple theories proposed, the exact etiology is still unclear. Diagnosis is straightforward, with radiographs and MRI aiding in it. While non-surgical treatment is recommended in most cases, in those warranting surgery, combined minimal-invasive techniques involving decompression of cyst and stabilization have gained importance in recent times. Conclusion There is variation in the diagnosis and treatment of UBCs among surgeons. Due to the vast heterogeneity of reported studies, no one method is the ideal standard of care. As most UBCs tend to resolve by skeletal maturity, clinicians need to balance the likelihood of successful treatment with morbidity associated with procedures and the risks of developing a pathological fracture. Study Design Review Article.
spellingShingle Rajasekaran, RB
Krishnamoorthy, V
Gulia, A
Unicameral bone cysts: review of etiopathogenesis and current concepts in diagnosis and management
title Unicameral bone cysts: review of etiopathogenesis and current concepts in diagnosis and management
title_full Unicameral bone cysts: review of etiopathogenesis and current concepts in diagnosis and management
title_fullStr Unicameral bone cysts: review of etiopathogenesis and current concepts in diagnosis and management
title_full_unstemmed Unicameral bone cysts: review of etiopathogenesis and current concepts in diagnosis and management
title_short Unicameral bone cysts: review of etiopathogenesis and current concepts in diagnosis and management
title_sort unicameral bone cysts review of etiopathogenesis and current concepts in diagnosis and management
work_keys_str_mv AT rajasekaranrb unicameralbonecystsreviewofetiopathogenesisandcurrentconceptsindiagnosisandmanagement
AT krishnamoorthyv unicameralbonecystsreviewofetiopathogenesisandcurrentconceptsindiagnosisandmanagement
AT guliaa unicameralbonecystsreviewofetiopathogenesisandcurrentconceptsindiagnosisandmanagement