Identification of the angiogenic gene signature induced by EGF and hypoxia in colorectal cancer.

BACKGROUND: Colorectal cancer (CRC) is characterised by hypoxia, which activates gene transcription through hypoxia-inducible factors (HIF), as well as by expression of epidermal growth factor (EGF) and EGF receptors, targeting of which has been demonstrated to provide therapeutic benefit in CRC. Al...

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Detaylı Bibliyografya
Asıl Yazarlar: Khong, T, Thairu, N, Larsen, H, Dawson, P, Kiriakidis, S, Paleolog, E
Materyal Türü: Journal article
Dil:English
Baskı/Yayın Bilgisi: BioMed Central 2013

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