Identification of the angiogenic gene signature induced by EGF and hypoxia in colorectal cancer.
BACKGROUND: Colorectal cancer (CRC) is characterised by hypoxia, which activates gene transcription through hypoxia-inducible factors (HIF), as well as by expression of epidermal growth factor (EGF) and EGF receptors, targeting of which has been demonstrated to provide therapeutic benefit in CRC. Al...
Asıl Yazarlar: | Khong, T, Thairu, N, Larsen, H, Dawson, P, Kiriakidis, S, Paleolog, E |
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Materyal Türü: | Journal article |
Dil: | English |
Baskı/Yayın Bilgisi: |
BioMed Central
2013
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