MRI brain T1 relaxation time changes in MS patients increase over time in both the white matter and the cortex.

OBJECTIVE: To test the sensitivity of whole-brain T1 relaxometry to the evolution of pathological changes in multiple sclerosis (MS). BACKGROUND: T1-weighted hypointense lesion load in the brains of patients with MS is associated with axonal loss. Other work has shown that T1 measurements may provi...

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Bibliographic Details
Main Authors: Parry, A, Clare, S, Jenkinson, M, Smith, S, Palace, J, Matthews, P
Format: Journal article
Language:English
Published: 2003