Different B cell subpopulations show distinct patterns in their IgH repertoire metrics

Several human B cell subpopulations are recognised in the peripheral blood, which play distinct roles in the humoral immune response. These cells undergo developmental and maturational changes involving VDJ recombination, somatic hypermutation and class switch recombination, altogether shaping their...

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Bibliografiske detaljer
Main Authors: Ghraichy, M, von Niederhäusern, V, Kovaltsuk, A, Galson, JD, Deane, CM, Trück, J
Format: Journal article
Sprog:English
Udgivet: eLife Sciences Publications 2021