Different B cell subpopulations show distinct patterns in their IgH repertoire metrics
Several human B cell subpopulations are recognised in the peripheral blood, which play distinct roles in the humoral immune response. These cells undergo developmental and maturational changes involving VDJ recombination, somatic hypermutation and class switch recombination, altogether shaping their...
Автори: | Ghraichy, M, von Niederhäusern, V, Kovaltsuk, A, Galson, JD, Deane, CM, Trück, J |
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Формат: | Journal article |
Мова: | English |
Опубліковано: |
eLife Sciences Publications
2021
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