Different B cell subpopulations show distinct patterns in their IgH repertoire metrics

Several human B cell subpopulations are recognised in the peripheral blood, which play distinct roles in the humoral immune response. These cells undergo developmental and maturational changes involving VDJ recombination, somatic hypermutation and class switch recombination, altogether shaping their...

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Détails bibliographiques
Auteurs principaux: Ghraichy, M, von Niederhäusern, V, Kovaltsuk, A, Galson, JD, Deane, CM, Trück, J
Format: Journal article
Langue:English
Publié: eLife Sciences Publications 2021