Different B cell subpopulations show distinct patterns in their IgH repertoire metrics

Several human B cell subpopulations are recognised in the peripheral blood, which play distinct roles in the humoral immune response. These cells undergo developmental and maturational changes involving VDJ recombination, somatic hypermutation and class switch recombination, altogether shaping their...

Полное описание

Библиографические подробности
Главные авторы: Ghraichy, M, von Niederhäusern, V, Kovaltsuk, A, Galson, JD, Deane, CM, Trück, J
Формат: Journal article
Язык:English
Опубликовано: eLife Sciences Publications 2021