Elucidating the chromosome 9 association with AS; CARD9 is a candidate gene.
Ankylosing spondylitis (AS) is polygenic with contributions from the immunologically relevant genes HLA-B*27, ERAP1 and IL23R. A recent genome-wide association screen (GWAS) identified associations (P approximately 0.005) with the non-synonymous single-nucleotide polymorphisms (nsSNPs), rs4077515 an...
Main Authors: | Pointon, J, Harvey, D, Karaderi, T, Appleton, L, Farrar, C, Stone, M, Sturrock, R, Brown, M, Wordsworth, B |
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Format: | Journal article |
Language: | English |
Published: |
2010
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