Anti-HIV IgA isotypes: differential virion capture and inhibition of transcytosis are linked to prevention of mucosal R5 SHIV transmission.

Anti-HIV IgA isotypes: differential virion capture and inhibition of transcytosis are linked to prevention of mucosal R5 SHIV transmission.

OBJECTIVE: Although passive immunization with anti-HIV-1 Env IgG1 neutralizing monoclonal antibodies (nmAbs) prevented simian-human immunodeficiency virus (SHIV) infection in rhesus monkeys, IgA nmAbs have not been tested. Here, we sought to determine whether human anti-HIV-1 dimeric (d)IgA1, dIgA2,...

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Bibliographic Details
Main Authors:	Watkins, J, Sholukh, A, Mukhtar, M, Siddappa, N, Lakhashe, S, Kim, M, Reinherz, E, Gupta, S, Forthal, D, Sattentau, Q, Villinger, F, Corti, D, Ruprecht, R
Format:	Journal article
Language:	English
Published:	2013

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