Delayed amputation following trauma increases residual lower limb infection.

INTRODUCTION: Residual limb infection following amputation is a devastating complication, resulting in delayed rehabilitation, repeat surgery, prolonged hospitalisation and poor functional outcome. The aim of this study was to identify variables predicting residual limb infection following non-salv...

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Main Authors: Jain, A, Glass, G, Ahmadi, H, Mackey, S, Simmons, J, Hettiaratchy, S, Pearse, M, Nanchahal, J
Format: Journal article
Language:English
Published: 2013
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author Jain, A
Glass, G
Ahmadi, H
Mackey, S
Simmons, J
Hettiaratchy, S
Pearse, M
Nanchahal, J
author_facet Jain, A
Glass, G
Ahmadi, H
Mackey, S
Simmons, J
Hettiaratchy, S
Pearse, M
Nanchahal, J
author_sort Jain, A
collection OXFORD
description INTRODUCTION: Residual limb infection following amputation is a devastating complication, resulting in delayed rehabilitation, repeat surgery, prolonged hospitalisation and poor functional outcome. The aim of this study was to identify variables predicting residual limb infection following non-salvageable lower limb trauma. METHODS: All cases of non-salvageable lower limb trauma presenting to a specialist centre over 5 years were evaluated from a prospective database and clinical and management variables correlated with the development of deep infection. RESULTS: Forty patients requiring 42 amputations were identified with a mean age of 49 years (±19.9, 1SD). Amputations were performed for 21 Gustilo IIIB injuries, 12 multi-planar degloving injuries, seven IIIC injuries and one open Schatzker 6 fracture. One limb was traumatically amputated at the scene and surgically revised. Amputation level was transtibial in 32, through-knee in one and transfemoral in nine. Median time from injury to amputation was 4 days (range 0-30 days). Amputation following only one debridement and within 5 days resulted in significantly fewer stump infections (p = 0.026 and p = 0.03, respectively, Fisher's exact test). The cumulative probability of infection-free residual limb closure declined steadily from day 5. Multivariate analyses revealed that neither the nature of the injury nor pre-injury patient morbidity independently influenced residual limb infection. CONCLUSION: Avoiding residual limb infection is critically dependent on prompt amputation of non-salvageable limbs.
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spelling oxford-uuid:1676cc54-25e0-4bfc-a9e2-82142b110c602022-03-26T10:31:32ZDelayed amputation following trauma increases residual lower limb infection.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:1676cc54-25e0-4bfc-a9e2-82142b110c60EnglishSymplectic Elements at Oxford2013Jain, AGlass, GAhmadi, HMackey, SSimmons, JHettiaratchy, SPearse, MNanchahal, J INTRODUCTION: Residual limb infection following amputation is a devastating complication, resulting in delayed rehabilitation, repeat surgery, prolonged hospitalisation and poor functional outcome. The aim of this study was to identify variables predicting residual limb infection following non-salvageable lower limb trauma. METHODS: All cases of non-salvageable lower limb trauma presenting to a specialist centre over 5 years were evaluated from a prospective database and clinical and management variables correlated with the development of deep infection. RESULTS: Forty patients requiring 42 amputations were identified with a mean age of 49 years (±19.9, 1SD). Amputations were performed for 21 Gustilo IIIB injuries, 12 multi-planar degloving injuries, seven IIIC injuries and one open Schatzker 6 fracture. One limb was traumatically amputated at the scene and surgically revised. Amputation level was transtibial in 32, through-knee in one and transfemoral in nine. Median time from injury to amputation was 4 days (range 0-30 days). Amputation following only one debridement and within 5 days resulted in significantly fewer stump infections (p = 0.026 and p = 0.03, respectively, Fisher's exact test). The cumulative probability of infection-free residual limb closure declined steadily from day 5. Multivariate analyses revealed that neither the nature of the injury nor pre-injury patient morbidity independently influenced residual limb infection. CONCLUSION: Avoiding residual limb infection is critically dependent on prompt amputation of non-salvageable limbs.
spellingShingle Jain, A
Glass, G
Ahmadi, H
Mackey, S
Simmons, J
Hettiaratchy, S
Pearse, M
Nanchahal, J
Delayed amputation following trauma increases residual lower limb infection.
title Delayed amputation following trauma increases residual lower limb infection.
title_full Delayed amputation following trauma increases residual lower limb infection.
title_fullStr Delayed amputation following trauma increases residual lower limb infection.
title_full_unstemmed Delayed amputation following trauma increases residual lower limb infection.
title_short Delayed amputation following trauma increases residual lower limb infection.
title_sort delayed amputation following trauma increases residual lower limb infection
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