Increasing inflationary T-cell responses following transient depletion of MCMV-specific memory T cells

Murine CMV (MCMV) infection induces effector CD8(+) T cells that continue to increase in frequency after acute infection ("inflation") and are stably maintained at a high frequency, with up to 20% of the CD8(+) T-cell compartment being specific for one epitope, although the flexibility and...

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Bibliographic Details
Main Authors: Sims, S, Bolinger, B, Klenerman, P
Format: Journal article
Language:English
Published: Wiley 2015