Lack of association of interferon regulatory factor 1 with severe malaria in affected child-parental trio studies across three African populations

Lack of association of interferon regulatory factor 1 with severe malaria in affected child-parental trio studies across three African populations

Interferon Regulatory Factor 1 (IRF-1) is a member of the IRF family of transcription factors, which have key and diverse roles in the gene-regulatory networks of the immune system. IRF-1 has been described as a critical mediator of IFN-gamma signalling and as the major player in driving TH1 type re...

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Bibliographic Details
Main Authors: Mangano, V, Clark, T, Auburn, S, Campino, S, Diakite, M, Fry, A, Green, A, Richardson, A, Jallow, M, Sisay-Joof, F, Pinder, M, Griffiths, M, Newton, C, Peshu, N, Williams, T, Marsh, K, Molyneux, M, Taylor, T, Modiano, D, Kwiatkowski, D, Rockett, K
Format: Journal article
Language:English
Published: 2009

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