Mutation of an influenza virus polymerase 3′ RNA promoter binding site inhibits transcription elongation

Mutation of an influenza virus polymerase 3′ RNA promoter binding site inhibits transcription elongation

<p>Influenza A virus encodes a viral RNA-dependent RNA polymerase (FluPol<sub>A</sub>), which is responsible for transcribing and replicating the negative-sense viral RNA (vRNA) genome. FluPol<sub>A</sub> transcribes vRNA using a host capped mRNA primer, and re...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Walker, A, Sharps, J, Fodor, E
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	American Society for Microbiology 2020

Παρόμοια τεκμήρια

Influenza virus inhibits RNA polymerase II elongation.
ανά: Chan, A, κ.ά.
Έκδοση: (2006)

A single amino acid mutation in the PA subunit of the influenza virus RNA polymerase inhibits endonucleolytic cleavage of capped RNAs.
ανά: Fodor, E, κ.ά.
Έκδοση: (2002)

The RNA polymerase of influenza a virus is stabilized by interaction with its viral RNA promoter.
ανά: Brownlee, G, κ.ά.
Έκδοση: (2002)

Interplay between influenza virus and the host RNA polymerase II transcriptional machinery
ανά: Walker, A, κ.ά.
Έκδοση: (2019)

Photochemical cross-linking of influenza A polymerase to its virion RNA promoter defines a polymerase binding site at residues 9 to 12 of the promoter.
ανά: Fodor, E, κ.ά.
Έκδοση: (1993)

Two aromatic residues in the PB2 subunit of influenza A RNA polymerase are crucial for cap binding.
ανά: Fechter, P, κ.ά.
Έκδοση: (2003)

The RNA polymerase of influenza a virus: mechanisms of viral transcription and replication.
ανά: Fodor, E
Έκδοση: (2013)

Mechanisms and functional implications of the degradation of host RNA polymerase II in influenza virus infected cells.
ανά: Vreede, F, κ.ά.
Έκδοση: (2010)

Phosphorylation controls RNA binding and transcription by the influenza virus polymerase.
ανά: Anthony R Dawson, κ.ά.
Έκδοση: (2020-09-01)

Mutational analysis of the PA and PB2 subunits of the influenza RNA polymerase complex leads to new insights into function
ανά: Fodor, E, κ.ά.
Έκδοση: (2004)

In vitro transcription and polymerase binding studies of the termini of influenza A virus cRNA: evidence for a cRNA panhandle.
ανά: Pritlove, D, κ.ά.
Έκδοση: (1995)

Direct Characterization of Transcription Elongation by RNA Polymerase I.
ανά: Suleyman Ucuncuoglu, κ.ά.
Έκδοση: (2016-01-01)

Role of the influenza virus heterotrimeric RNA polymerase complex in the initiation of replication.
ανά: Deng, T, κ.ά.
Έκδοση: (2006)

Association of the influenza A virus RNA-dependent RNA polymerase with cellular RNA polymerase II.
ανά: Engelhardt, O, κ.ά.
Έκδοση: (2005)

Structures of influenza A virus RNA polymerase offer insight into viral genome replication
ανά: Fan, H, κ.ά.
Έκδοση: (2019)

Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies
ανά: Keown, J, κ.ά.
Έκδοση: (2022)

RNA-free and ribonucleoprotein-associated influenza virus polymerases directly bind the serine-5 phosphorylated carboxyl-terminal domain of host RNA polymerase II
ανά: Fodor, E, κ.ά.
Έκδοση: (2016)

Regulation of elongating RNA polymerase II by forkhead transcription factors in yeast.
ανά: Morillon, A, κ.ά.
Έκδοση: (2003)

Comparison of Transcription Elongation Rates of Three RNA Polymerases in Real Time
ανά: Priyanka Tare, κ.ά.
Έκδοση: (2023-12-01)

Stimulation of transcript elongation requires both the zinc finger and RNA polymerase II binding domains of human TFIIS
ανά: Agarwal, Kan, κ.ά.
Έκδοση: (2012)

A single amino acid mutation in the PA subunit of the influenza virus RNA polymerase promotes the generation of defective interfering RNAs.
ανά: Fodor, E, κ.ά.
Έκδοση: (2003)

Regulation of RNA Polymerase II Transcription Initiation and Elongation by Transcription Factor TFII-I
ανά: Niko Linzer, κ.ά.
Έκδοση: (2021-05-01)

Uncoupling of influenza A virus transcription and replication through mutation of the unpaired adenosine in the viral RNA promoter.
ανά: te Velthuis, A, κ.ά.
Έκδοση: (2013)

Influenza virus RNA polymerase: insights into the mechanisms of viral RNA synthesis
ανά: Fodor, E, κ.ά.
Έκδοση: (2016)

The role of the influenza virus RNA polymerase in host shut-off.
ανά: Vreede, F, κ.ά.
Έκδοση: (2010)

Influenza virus mounts a two-pronged attack on host RNA polymerase II transcription
ανά: Bauer, D, κ.ά.
Έκδοση: (2018)

The surface-exposed PA51-72-loop of the influenza A virus polymerase is required for viral genome replication
ανά: Nilsson-Payant, B, κ.ά.
Έκδοση: (2018)

Uncovering the mechanisms of transcription elongation by eukaryotic RNA polymerases I, II, and III
ανά: Ruth Q. Jacobs, κ.ά.
Έκδοση: (2022-11-01)

The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicing.
ανά: Yehuda Brody, κ.ά.
Έκδοση: (2011-01-01)

Role of ran binding protein 5 in nuclear import and assembly of the influenza virus RNA polymerase complex.
ανά: Deng, T, κ.ά.
Έκδοση: (2006)

Pause sites promote transcriptional termination of mammalian RNA polymerase II.
ανά: Gromak, N, κ.ά.
Έκδοση: (2006)

The C-terminal domains of the PB2 subunit of the influenza A virus RNA polymerase directly interact with cellular GTPase Rab11a
ανά: Veler, H, κ.ά.
Έκδοση: (2022)

Architecture of the RNA polymerase II-Paf1C-TFIIS transcription elongation complex
ανά: Youwei Xu, κ.ά.
Έκδοση: (2017-06-01)

Characterizing intergenic transcription at RNA polymerase II binding sites in normal and cancer tissues
ανά: Pierre de Langen, κ.ά.
Έκδοση: (2023-10-01)

Differential role of the influenza A virus polymerase PA subunit for vRNA and cRNA promoter binding.
ανά: Maier, H, κ.ά.
Έκδοση: (2008)

Gdown1 Associates Efficiently with RNA Polymerase II after Promoter Clearance and Displaces TFIIF during Transcript Elongation.
ανά: Elizabeth DeLaney, κ.ά.
Έκδοση: (2016-01-01)

Attenuation of influenza A virus mRNA levels by promoter mutations.
ανά: Fodor, E, κ.ά.
Έκδοση: (1998)

Single-molecule FRET reveals a corkscrew RNA structure for the polymerase-bound influenza virus promoter.
ανά: Tomescu, A, κ.ά.
Έκδοση: (2014)

Anthralin Suppresses the Proliferation of Influenza Virus by Inhibiting the Cap-Binding and Endonuclease Activity of Viral RNA Polymerase
ανά: Ao Hu, κ.ά.
Έκδοση: (2020-02-01)

Characterizing Influenza a RNA Polymerase - Promoter Interaction using Ensemble Fluorescence Spectroscopy
ανά: Tomescu, A, κ.ά.
Έκδοση: (2013)