Mutation of an influenza virus polymerase 3′ RNA promoter binding site inhibits transcription elongation

<p>Influenza A virus encodes a viral RNA-dependent RNA polymerase (FluPol<sub>A</sub>), which is responsible for transcribing and replicating the negative-sense viral RNA (vRNA) genome. FluPol<sub>A</sub>&nbsp;transcribes vRNA using a host capped mRNA primer, and re...

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Hlavní autoři: Walker, A, Sharps, J, Fodor, E
Médium: Journal article
Jazyk:English
Vydáno: American Society for Microbiology 2020