Uncommon CHEK2 mis-sense variant and reduced risk of tobacco-related cancers: case control study.
CHEK2 is a key cell cycle control gene encoding a pluripotent kinase that can cause arrest or apoptosis in response to unrepaired DNA damage. We report a large case-control study of a non-functional variant that had previously been expected to increase cancer rates. Four thousand and fifteen cancer...
প্রধান লেখক: | , , , , , , , , , , , , , , , , , , , , , , , , |
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বিন্যাস: | Journal article |
ভাষা: | English |
প্রকাশিত: |
2007
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