Uncommon CHEK2 mis-sense variant and reduced risk of tobacco-related cancers: case control study.

CHEK2 is a key cell cycle control gene encoding a pluripotent kinase that can cause arrest or apoptosis in response to unrepaired DNA damage. We report a large case-control study of a non-functional variant that had previously been expected to increase cancer rates. Four thousand and fifteen cancer...

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Dettagli Bibliografici
Autori principali:	Brennan, P, McKay, J, Moore, L, Zaridze, D, Mukeria, A, Szeszenia-Dabrowska, N, Lissowska, J, Rudnai, P, Fabianova, E, Mates, D, Bencko, V, Foretova, L, Janout, V, Chow, W, Rothman, N, Chabrier, A, Gaborieau, V, Odefrey, F, Southey, M, Hashibe, M, Hall, J, Boffetta, P, Peto, J, Peto, R, Hung, R
Natura:	Journal article
Lingua:	English
Pubblicazione:	2007

Uncommon CHEK2 mis-sense variant and reduced risk of tobacco-related cancers: case control study.

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