Nonimmunogenic tumor cells may efficiently restimulate tumor antigen-specific cytotoxic T cells.

Induction of immunity to a viral protein that had been transfected into a tumor cell line was studied. The nucleoprotein (NP) of vesicular stomatitis virus (VSV) was used as a model tumor-associated Ag after transfection into EL-4, and H-2b thymoma originating from C57BL/6 mice. The NP-transfected c...

ver descrição completa

Detalhes bibliográficos
Principais autores: Kündig, T, Bachmann, M, Lefrancois, L, Puddington, L, Hengartner, H, Zinkernagel, R
Formato: Journal article
Idioma:English
Publicado em: 1993