Structural characterisation of amorphous solid dispersions via metropolis matrix factorisation of pair distribution function data

We measure the X-ray pair distribution functions (PDFs) of a series of felodipine:copovidone amorphous solid dispersions. Using a newly-developed Metropolis Matrix Factorisation (MMF) algorithm we extract from these data the PDF of the amorphous felodipine component in isolation. Our MMF analysis al...

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Main Authors: Geddes, H, Blade, H, McCabe, J, Hughes, L, Goodwin, A
格式: Journal article
语言:English
出版: Royal Society of Chemistry 2019