Pro-inflammatory polarization and colorectal cancer modulate alternative and intronic polyadenylation in primary human macrophages
<p><strong>Introduction:</strong> Macrophages are essential cells of the immune system that alter their inflammatory profile depending on their microenvironment. Alternative polyadenylation in the 3’UTR (3’UTR-APA) and intronic polyadenylation (IPA) are mechanisms that modulate gen...
Main Authors: | Wilton, J, de Mendonça, FL, Pereira-Castro, I, Tellier, M, Nojima, T, Costa, AM, Freitas, J, Murphy, S, Oliveira, MJ, Proudfoot, NJ, Moreira, A |
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Format: | Journal article |
Language: | English |
Published: |
Frontiers Media
2023
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