An essential role for the Zn2+ transporter ZIP7 in B cell development

An essential role for the Zn2+ transporter ZIP7 in B cell development

Despite the known importance of zinc for human immunity, molecular insights into its roles have remained limited. Here we report a novel autosomal recessive disease characterized by absent B cells, agammaglobulinemia and early onset infections in five unrelated families. The immunodeficiency results...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Anzilotti, C, Swan, D, Boisson, B, Deobagkar-Lele, M, Oliveira, C, Chabosseau, P, Englehardt, K, Xu, X, Chen, R, Alvarez, L, Berlinguer-Palmini, R, Bull, K, Cawthorne, E, Cribbs, A, Crockford, T, Dang, T, Fearn, A, Fenech, E, de Jong, S, Lagerholm, B, Ma, C, Sims, D, van den Berg, B, Xu, Y, Cant, A, Kleiner, G, Leahy, T, de la Morena, M, Puck, J, Shapiro, R, van der Burg, M, Chapman, J, Christianson, J, Davies, B, McGrath, J, Przyborski, S, Santibanez Koref, M, Tangye, S, Werner, A, Rutter, G, Padilla-Parra, S, Casanova, J, Cornall, R, Conley, M, Hambleton, S
التنسيق: Journal article
منشور في: Nature Publishing Group 2019

مواد مشابهة

مواد مشابهة