A hydrogen-driven biocatalytic approach to recycling synthetic analogues of NAD(P)H
We demonstrate a recycling system for synthetic nicotinamide cofactor analogues using a soluble hydrogenase with turnover number of >1000 for reduction of the cofactor analogues by H2. Coupling this system to an ene reductase, we show quantitative conversion of N-ethylmaleimide to N-ethylsuccinim...
Full description
Bibliographic Details
| Main Authors: |
Reeve, HA,
Nicholson, J,
Altaf, F,
Lonsdale, TH,
Preissler, J,
Lauterbach, L,
Lenz, O,
Leimkühler, S,
Hollmann, F,
Paul, CE,
Vincent, KA |
|---|
| Format: | Journal article
|
|---|
| Language: | English |
|---|
| Published: |
Royal Society of Chemistry
2022
|
|---|