A novel meningococcal outer membrane vesicle vaccine with constitutive expression of FetA: A phase I clinical trial.

OBJECTIVES: Outer membrane vesicle (OMV) vaccines are used against outbreaks of capsular group B Neisseria meningitidis (MenB) caused by strains expressing particular PorA outer membrane proteins (OMPs). Ferric enterobactin receptor (FetA) is another variable OMP that induces type-specific bacterici...

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Détails bibliographiques
Auteurs principaux: Marsay, L, Dold, C, Green, C, Rollier, C, Norheim, G, Sadarangani, M, Shanyinde, M, Brehony, C, Thompson, A, Sanders, H, Chan, H, Haworth, K, Derrick, J, Feavers, I, Maiden, M, Pollard, A
Format: Journal article
Langue:English
Publié: Elsevier 2015