Pharmacological FMRI: measuring opioid effects on the BOLD response to hypercapnia.
Opioid binding to the cerebral blood vessels may affect vascular responsiveness and hence confound interpretation of blood oxygen level-dependent (BOLD) responses, which are usually interpreted as neuronal in origin. Opioid binding varies in different brain regions. It is unclear whether opioids alt...
Main Authors: | Pattinson, K, Rogers, R, Mayhew, S, Tracey, I, Wise, R |
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Format: | Journal article |
Language: | English |
Published: |
2007
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