Generating the evidence for typhoid vaccine introduction: Considerations for global disease burden estimates and vaccine testing through human challenge

Typhoid fever has had a major impact on human populations, with the causative pathogen Salmonella enterica serovar Typhi implicated in many outbreaks through history. The current burden of disease is estimated at 11–18 million infections annually, with the majority of infections located in Africa an...

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Bibliographic Details
Main Authors: Meiring, J, Giubilini, A, Savulescu, J, Pitzer, V, Pollard, A
Format: Journal article
Language:English
Published: Oxford University Press 2019