What do we need to know and understand about p53 to improve its clinical value?

Few proteins are more studied than the p53 tumour suppressor, but what have we learned from these studies and what do we really know about p53 that can benefit clinical practice? The DNA sequence encoding p53 is frequently mutated in cancers but the functional outcomes of single mutations, in respec...

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Détails bibliographiques
Auteurs principaux: Salomao, N, Karakostis, K, Hupp, T, Vollrath, F, Vojtesek, B, Fahraeus, R
Format: Journal article
Langue:English
Publié: Wiley 2021