Enriched HLA-E and CD94/NKG2A interaction limits antitumor CD8+ tumor-infiltrating T lymphocyte responses

Enriched HLA-E and CD94/NKG2A interaction limits antitumor CD8+ tumor-infiltrating T lymphocyte responses

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Immunotherapy treatments with anti-PD-1 boost recovery in less than 30% of treated cancer patients, indicating the complexity of the tumor microenvironment. Expression of HLA-E is linked to poor clinical outcomes in mice and human patients. However, the contributions to immune evasion of HLA-E, a li...

Podrobná bibliografie
Hlavní autoři:	Abd Hamid, M, Wang, R, Yao, X, Fan, P, Li, X, Chang, X, Feng, Y, Jones, S, Maldonado-Perez, D, Waugh, C, Verrill, C, Simmons, A, Cerundolo, V, McMichael, A, Conlon, C, Wang, X, Peng, Y, Dong, T
Médium:	Journal article
Jazyk:	English
Vydáno:	American Association for Cancer Research 2019

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