Enriched HLA-E and CD94/NKG2A interaction limits antitumor CD8+ tumor-infiltrating T lymphocyte responses

Enriched HLA-E and CD94/NKG2A interaction limits antitumor CD8+ tumor-infiltrating T lymphocyte responses

他のバージョン（1件）を表示する

Immunotherapy treatments with anti-PD-1 boost recovery in less than 30% of treated cancer patients, indicating the complexity of the tumor microenvironment. Expression of HLA-E is linked to poor clinical outcomes in mice and human patients. However, the contributions to immune evasion of HLA-E, a li...

書誌詳細
主要な著者:	Abd Hamid, M, Wang, R, Yao, X, Fan, P, Li, X, Chang, X, Feng, Y, Jones, S, Maldonado-Perez, D, Waugh, C, Verrill, C, Simmons, A, Cerundolo, V, McMichael, A, Conlon, C, Wang, X, Peng, Y, Dong, T
フォーマット:	Journal article
言語:	English
出版事項:	American Association for Cancer Research 2019

類似資料

Enriched HLA-E and CD94/NKG2a interaction limits anti-tumor CD8+ tumor-infiltrating T lymphocyte responses
著者:: Abd Hamid, M, 等
出版事項: (2019)

HLA-E is expressed on trophoblast and interacts with CD94/NKG2 receptors on decidual NK cells.
著者:: King, A, 等
出版事項: (2000)

HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C.
著者:: Braud, V, 等
出版事項: (1998)

Regulation of NK cell functions through interaction of the CD94/NKG2 receptors with the nonclassical class I molecule HLA-E.
著者:: Braud, V, 等
出版事項: (1999)

HLA class I signal peptide polymorphism determines the level of CD94/NKG2–HLA-E-mediated regulation of effector cell responses
著者:: Lin, Z, 等
出版事項: (2023)

High-throughput characterization of HLA-E-presented CD94/NKG2x ligands reveals peptides which modulate NK cell activation
著者:: Huisman, BD, 等
出版事項: (2023)

A signal peptide derived from hsp60 binds HLA-E and interferes with CD94/NKG2A recognition.
著者:: Michaëlsson, J, 等
出版事項: (2002)

High-throughput characterization of HLA-E-presented CD94/NKG2x ligands reveals peptides which modulate NK cell activation
著者:: Brooke D. Huisman, 等
出版事項: (2023-08-01)

CD94/NKG2 is the predominant inhibitory receptor involved in recognition of HLA-G by decidual and peripheral blood NK cells.
著者:: Söderström, K, 等
出版事項: (1997)

Natural killer cell surveillance of intracellular antigen processing pathways mediated by recognition of HLA-E and Qa-1b by CD94/NKG2 receptors.
著者:: O'Callaghan, C
出版事項: (2000)

Publisher Correction: High-throughput characterization of HLA-E-presented CD94/NKG2x ligands reveals peptides which modulate NK cell activation
著者:: Brooke D. Huisman, 等
出版事項: (2023-08-01)

CD94-driven in vitro expansion of highly functional adaptive NKG2C+ NKG2A- CD57+ NK cells from CMV+ healthy donors
著者:: Chiara Giordano, 等
出版事項: (2025-01-01)

Targeting LAG‐3 restores CD8+ T cell effector function through CD94/NKG2‐Qa‐1b signaling
著者:: Zhiqiang Wang, 等
出版事項: (2024-12-01)

Immune checkpoints HLA-E:CD94-NKG2A and HLA-C:KIR2DL1 complementarily shield circulating tumor cells from NK-mediated immune surveillance
著者:: Xiaowei Liu, 等
出版事項: (2024-02-01)

Combinatorial HLA-peptide bead libraries for high throughput identification of CD8⁺ T cell specificity.
著者:: Pan, X, 等
出版事項: (2014)

Combinatorial HLA-peptide bead libraries for high throughput identification of CD8+ T cell specificity
著者:: Pan, X, 等
出版事項: (2014)

A comprehensive analysis of key immune checkpoint receptors on tumor-infiltrating T cells from multiple types of cancer
著者:: Li, X, 等
出版事項: (2019)

What a Difference an Amino Acid Makes: An All-Atom Simulation Study of Nonameric Peptides in Inhibitory HLA-E/NKG2A/CD94 Immune Complexes
著者:: Eva Prašnikar, 等
出版事項: (2022-08-01)

Self-maintaining CD103+ cancer-specific T cells are highly energetic with rapid cytotoxic and effector responses
著者:: Abd Hamid, M, 等
出版事項: (2019)

High-Density of FcγRIIIA+ (CD16+) Tumor-Associated Neutrophils in Metastases Improves the Therapeutic Response of Cetuximab in Metastatic Colorectal Cancer Patients, Independently of the HLA-E/CD94-NKG2A Axis
著者:: Marie Denis Musquer, 等
出版事項: (2021-06-01)

502 Discovery of HX017, a novel NKG2A/CD94 mAb, for potential cancer immunotherapy
著者:: Faming Zhang, 等
出版事項: (2023-11-01)

A Conserved HIV-1-Derived Peptide Presented by HLA-E Renders Infected T-cells Highly Susceptible to Attack by NKG2A/CD94-Bearing Natural Killer Cells.
著者:: Zachary B Davis, 等
出版事項: (2016-02-01)

Activating and inhibitory receptors on synovial fluid natural killer cells of arthritis patients: role of CD94/NKG2A in control of cytokine secretion.
著者:: de Matos, C, 等
出版事項: (2007)

Differential expression of NK receptors CD94 and NKG2A by T cells in rheumatoid arthritis patients in remission compared to active disease.
著者:: Ceara E Walsh, 等
出版事項: (2011-01-01)

Activated NK cells reprogram MDSCs via NKG2D-NKG2DL and IFN-γ to modulate antitumor T-cell response after cryo-thermal therapy
著者:: Peng Peng, 等
出版事項: (2022-12-01)

CD8+ T lymphocytes are sensitive to NKG2A/HLA-E licensing interaction: role in the survival of cancer patients
著者:: Lourdes Gimeno, 等
出版事項: (2021-01-01)

A herpesvirus encoded Qa-1 mimic inhibits natural killer cell cytotoxicity through CD94/NKG2A receptor engagement
著者:: Xiaoli Wang, 等
出版事項: (2018-12-01)

Balance between activating NKG2D, DNAM-1, NKp44 and NKp46 and inhibitory CD94/NKG2A receptors determine natural killer degranulation towards rheumatoid arthritis synovial fibroblasts.
著者:: Nielsen, N, 等
出版事項: (2014)

PD-1 expression status on CD8+ tumour infiltrating lymphocytes associates with survival in cervical cancer
著者:: Fan, P, 等
出版事項: (2020)

LAYN Serves as a Prognostic Biomarker and Downregulates Tumor-Infiltrating CD8+ T Cell Function in Hepatocellular Carcinoma
著者:: Xiao S, 等
出版事項: (2024-06-01)

Downregulation of CD94/NKG2A inhibitory receptors on CD8<sup>+ </sup>T cells in HIV infection is more pronounced in subjects with detected viral load than in their aviraemic counterparts
著者:: Vaira Dolores, 等
出版事項: (2007-10-01)

Targeting CD93 on monocytes revitalizes antitumor immunity by enhancing the function and infiltration of CD8+ T cells
著者:: Yan Wu, 等
出版事項: (2024-10-01)

The MHC-E peptide ligands for checkpoint CD94/NKG2A are governed by inflammatory signals, whereas LILRB1/2 receptors are peptide indifferent
著者:: Jim Middelburg, 等
出版事項: (2023-12-01)

Elusive Role of the CD94/NKG2C NK Cell Receptor in the Response to Cytomegalovirus: Novel Experimental Observations in a Reporter Cell System
著者:: Aldi Pupuleku, 等
出版事項: (2017-10-01)

IL‐15‐induced CD38+HLA‐DR+CD8+ T cells correlate with liver injury via NKG2D in chronic hepatitis B cirrhosis
著者:: Jing Fan, 等
出版事項: (2024-01-01)

IFN-gamma protects short-term ovarian carcinoma cell lines from CTL lysis via a CD94/NKG2A-dependent mechanism.
著者:: Malmberg, K, 等
出版事項: (2002)

CD8A is a Promising Biomarker Associated with Immunocytes Infiltration in Hyperoxia-Induced Bronchopulmonary Dysplasia
著者:: Du Y, 等
出版事項: (2023-04-01)

HIV-1 down-regulates the expression of CD1d via Nef.
著者:: Chen, N, 等
出版事項: (2006)

CD1B is a Potential Prognostic Biomarker Associated with Tumor Mutation Burden and Promotes Antitumor Immunity in Lung Adenocarcinoma
著者:: Li Z, 等
出版事項: (2022-04-01)

Bispecific NKG2D-CD3 and NKG2D-CD16 Fusion Proteins as Novel Treatment Option in Advanced Soft Tissue Sarcomas
著者:: Ilona Hagelstein, 等
出版事項: (2021-04-01)