Enriched HLA-E and CD94/NKG2A interaction limits antitumor CD8+ tumor-infiltrating T lymphocyte responses

Enriched HLA-E and CD94/NKG2A interaction limits antitumor CD8+ tumor-infiltrating T lymphocyte responses

Бусад хувилбаруудыг харуулах (1)

Immunotherapy treatments with anti-PD-1 boost recovery in less than 30% of treated cancer patients, indicating the complexity of the tumor microenvironment. Expression of HLA-E is linked to poor clinical outcomes in mice and human patients. However, the contributions to immune evasion of HLA-E, a li...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Abd Hamid, M, Wang, R, Yao, X, Fan, P, Li, X, Chang, X, Feng, Y, Jones, S, Maldonado-Perez, D, Waugh, C, Verrill, C, Simmons, A, Cerundolo, V, McMichael, A, Conlon, C, Wang, X, Peng, Y, Dong, T
Формат:	Journal article
Хэл сонгох:	English
Хэвлэсэн:	American Association for Cancer Research 2019

Ижил төстэй зүйлс

Enriched HLA-E and CD94/NKG2a interaction limits anti-tumor CD8+ tumor-infiltrating T lymphocyte responses
-н: Abd Hamid, M, зэрэг
Хэвлэсэн: (2019)

HLA-E is expressed on trophoblast and interacts with CD94/NKG2 receptors on decidual NK cells.
-н: King, A, зэрэг
Хэвлэсэн: (2000)

HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C.
-н: Braud, V, зэрэг
Хэвлэсэн: (1998)

Regulation of NK cell functions through interaction of the CD94/NKG2 receptors with the nonclassical class I molecule HLA-E.
-н: Braud, V, зэрэг
Хэвлэсэн: (1999)

HLA class I signal peptide polymorphism determines the level of CD94/NKG2–HLA-E-mediated regulation of effector cell responses
-н: Lin, Z, зэрэг
Хэвлэсэн: (2023)

High-throughput characterization of HLA-E-presented CD94/NKG2x ligands reveals peptides which modulate NK cell activation
-н: Huisman, BD, зэрэг
Хэвлэсэн: (2023)

A signal peptide derived from hsp60 binds HLA-E and interferes with CD94/NKG2A recognition.
-н: Michaëlsson, J, зэрэг
Хэвлэсэн: (2002)

High-throughput characterization of HLA-E-presented CD94/NKG2x ligands reveals peptides which modulate NK cell activation
-н: Brooke D. Huisman, зэрэг
Хэвлэсэн: (2023-08-01)

CD94/NKG2 is the predominant inhibitory receptor involved in recognition of HLA-G by decidual and peripheral blood NK cells.
-н: Söderström, K, зэрэг
Хэвлэсэн: (1997)

Natural killer cell surveillance of intracellular antigen processing pathways mediated by recognition of HLA-E and Qa-1b by CD94/NKG2 receptors.
-н: O'Callaghan, C
Хэвлэсэн: (2000)

Publisher Correction: High-throughput characterization of HLA-E-presented CD94/NKG2x ligands reveals peptides which modulate NK cell activation
-н: Brooke D. Huisman, зэрэг
Хэвлэсэн: (2023-08-01)

CD94-driven in vitro expansion of highly functional adaptive NKG2C+ NKG2A- CD57+ NK cells from CMV+ healthy donors
-н: Chiara Giordano, зэрэг
Хэвлэсэн: (2025-01-01)

Targeting LAG‐3 restores CD8+ T cell effector function through CD94/NKG2‐Qa‐1b signaling
-н: Zhiqiang Wang, зэрэг
Хэвлэсэн: (2024-12-01)

Immune checkpoints HLA-E:CD94-NKG2A and HLA-C:KIR2DL1 complementarily shield circulating tumor cells from NK-mediated immune surveillance
-н: Xiaowei Liu, зэрэг
Хэвлэсэн: (2024-02-01)

Combinatorial HLA-peptide bead libraries for high throughput identification of CD8⁺ T cell specificity.
-н: Pan, X, зэрэг
Хэвлэсэн: (2014)

Combinatorial HLA-peptide bead libraries for high throughput identification of CD8+ T cell specificity
-н: Pan, X, зэрэг
Хэвлэсэн: (2014)

What a Difference an Amino Acid Makes: An All-Atom Simulation Study of Nonameric Peptides in Inhibitory HLA-E/NKG2A/CD94 Immune Complexes
-н: Eva Prašnikar, зэрэг
Хэвлэсэн: (2022-08-01)

A comprehensive analysis of key immune checkpoint receptors on tumor-infiltrating T cells from multiple types of cancer
-н: Li, X, зэрэг
Хэвлэсэн: (2019)

Self-maintaining CD103+ cancer-specific T cells are highly energetic with rapid cytotoxic and effector responses
-н: Abd Hamid, M, зэрэг
Хэвлэсэн: (2019)

High-Density of FcγRIIIA+ (CD16+) Tumor-Associated Neutrophils in Metastases Improves the Therapeutic Response of Cetuximab in Metastatic Colorectal Cancer Patients, Independently of the HLA-E/CD94-NKG2A Axis
-н: Marie Denis Musquer, зэрэг
Хэвлэсэн: (2021-06-01)

502 Discovery of HX017, a novel NKG2A/CD94 mAb, for potential cancer immunotherapy
-н: Faming Zhang, зэрэг
Хэвлэсэн: (2023-11-01)

A Conserved HIV-1-Derived Peptide Presented by HLA-E Renders Infected T-cells Highly Susceptible to Attack by NKG2A/CD94-Bearing Natural Killer Cells.
-н: Zachary B Davis, зэрэг
Хэвлэсэн: (2016-02-01)

Activating and inhibitory receptors on synovial fluid natural killer cells of arthritis patients: role of CD94/NKG2A in control of cytokine secretion.
-н: de Matos, C, зэрэг
Хэвлэсэн: (2007)

Differential expression of NK receptors CD94 and NKG2A by T cells in rheumatoid arthritis patients in remission compared to active disease.
-н: Ceara E Walsh, зэрэг
Хэвлэсэн: (2011-01-01)

Activated NK cells reprogram MDSCs via NKG2D-NKG2DL and IFN-γ to modulate antitumor T-cell response after cryo-thermal therapy
-н: Peng Peng, зэрэг
Хэвлэсэн: (2022-12-01)

CD8+ T lymphocytes are sensitive to NKG2A/HLA-E licensing interaction: role in the survival of cancer patients
-н: Lourdes Gimeno, зэрэг
Хэвлэсэн: (2021-01-01)

A herpesvirus encoded Qa-1 mimic inhibits natural killer cell cytotoxicity through CD94/NKG2A receptor engagement
-н: Xiaoli Wang, зэрэг
Хэвлэсэн: (2018-12-01)

Balance between activating NKG2D, DNAM-1, NKp44 and NKp46 and inhibitory CD94/NKG2A receptors determine natural killer degranulation towards rheumatoid arthritis synovial fibroblasts.
-н: Nielsen, N, зэрэг
Хэвлэсэн: (2014)

PD-1 expression status on CD8+ tumour infiltrating lymphocytes associates with survival in cervical cancer
-н: Fan, P, зэрэг
Хэвлэсэн: (2020)

LAYN Serves as a Prognostic Biomarker and Downregulates Tumor-Infiltrating CD8+ T Cell Function in Hepatocellular Carcinoma
-н: Xiao S, зэрэг
Хэвлэсэн: (2024-06-01)

Downregulation of CD94/NKG2A inhibitory receptors on CD8<sup>+ </sup>T cells in HIV infection is more pronounced in subjects with detected viral load than in their aviraemic counterparts
-н: Vaira Dolores, зэрэг
Хэвлэсэн: (2007-10-01)

Targeting CD93 on monocytes revitalizes antitumor immunity by enhancing the function and infiltration of CD8+ T cells
-н: Yan Wu, зэрэг
Хэвлэсэн: (2024-10-01)

The MHC-E peptide ligands for checkpoint CD94/NKG2A are governed by inflammatory signals, whereas LILRB1/2 receptors are peptide indifferent
-н: Jim Middelburg, зэрэг
Хэвлэсэн: (2023-12-01)

Elusive Role of the CD94/NKG2C NK Cell Receptor in the Response to Cytomegalovirus: Novel Experimental Observations in a Reporter Cell System
-н: Aldi Pupuleku, зэрэг
Хэвлэсэн: (2017-10-01)

CD8A is a Promising Biomarker Associated with Immunocytes Infiltration in Hyperoxia-Induced Bronchopulmonary Dysplasia
-н: Du Y, зэрэг
Хэвлэсэн: (2023-04-01)

IL‐15‐induced CD38+HLA‐DR+CD8+ T cells correlate with liver injury via NKG2D in chronic hepatitis B cirrhosis
-н: Jing Fan, зэрэг
Хэвлэсэн: (2024-01-01)

IFN-gamma protects short-term ovarian carcinoma cell lines from CTL lysis via a CD94/NKG2A-dependent mechanism.
-н: Malmberg, K, зэрэг
Хэвлэсэн: (2002)

CD1B is a Potential Prognostic Biomarker Associated with Tumor Mutation Burden and Promotes Antitumor Immunity in Lung Adenocarcinoma
-н: Li Z, зэрэг
Хэвлэсэн: (2022-04-01)

HIV-1 down-regulates the expression of CD1d via Nef.
-н: Chen, N, зэрэг
Хэвлэсэн: (2006)

Correction: Targeting CD93 on monocytes revitalizes antitumor immunity by enhancing the function and infiltration of CD8+ T cells
Хэвлэсэн: (2024-11-01)