Enriched HLA-E and CD94/NKG2A interaction limits antitumor CD8+ tumor-infiltrating T lymphocyte responses
Immunotherapy treatments with anti-PD-1 boost recovery in less than 30% of treated cancer patients, indicating the complexity of the tumor microenvironment. Expression of HLA-E is linked to poor clinical outcomes in mice and human patients. However, the contributions to immune evasion of HLA-E, a li...
Main Authors: | Abd Hamid, M, Wang, R, Yao, X, Fan, P, Li, X, Chang, X, Feng, Y, Jones, S, Maldonado-Perez, D, Waugh, C, Verrill, C, Simmons, A, Cerundolo, V, McMichael, A, Conlon, C, Wang, X, Peng, Y, Dong, T |
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格式: | Journal article |
語言: | English |
出版: |
American Association for Cancer Research
2019
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