Does idiopathic parkinsonism in Aberdeen follow intrauterine influenza?

A study is presented which fails to replicate a recent report that peak years of birth of patients later developing Parkinson's disease are related to the influenza pandemics of the period 1890-1930. The years of birth of a whole population cohort of 243 patients suffering from Parkinson's...

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Main Authors: Ebmeier, K, Mutch, W, Calder, SA, Crawford, JR, Stewart, L, Besson, J
Format: Journal article
Language:English
Published: 1989
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author Ebmeier, K
Mutch, W
Calder, SA
Crawford, JR
Stewart, L
Besson, J
author_facet Ebmeier, K
Mutch, W
Calder, SA
Crawford, JR
Stewart, L
Besson, J
author_sort Ebmeier, K
collection OXFORD
description A study is presented which fails to replicate a recent report that peak years of birth of patients later developing Parkinson's disease are related to the influenza pandemics of the period 1890-1930. The years of birth of a whole population cohort of 243 patients suffering from Parkinson's disease examined in Aberdeen in 1983 and reexamined in 1986/7 were compared with deaths due to influenza in the City of Aberdeen in the years 1900-1930. Although a significant peak of Parkinson births (compared with the age profile of the Aberdeen population in 1983) occurred in 1902, there appeared to be no systematic relationship between Parkinson births and influenza deaths. In addition, no season of birth effect could be detected in a comparison with 232 matched controls. The presence of peaks of birth years, for whatever aetiological reason, is of significance to epidemiological studies in that prevalence estimates may be influenced by the year of study relative to these mini-cohorts.
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spelling oxford-uuid:17db4ab9-5bde-4a77-bd8c-a681c6fbec352022-03-26T10:39:49ZDoes idiopathic parkinsonism in Aberdeen follow intrauterine influenza?Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:17db4ab9-5bde-4a77-bd8c-a681c6fbec35EnglishSymplectic Elements at Oxford1989Ebmeier, KMutch, WCalder, SACrawford, JRStewart, LBesson, JA study is presented which fails to replicate a recent report that peak years of birth of patients later developing Parkinson's disease are related to the influenza pandemics of the period 1890-1930. The years of birth of a whole population cohort of 243 patients suffering from Parkinson's disease examined in Aberdeen in 1983 and reexamined in 1986/7 were compared with deaths due to influenza in the City of Aberdeen in the years 1900-1930. Although a significant peak of Parkinson births (compared with the age profile of the Aberdeen population in 1983) occurred in 1902, there appeared to be no systematic relationship between Parkinson births and influenza deaths. In addition, no season of birth effect could be detected in a comparison with 232 matched controls. The presence of peaks of birth years, for whatever aetiological reason, is of significance to epidemiological studies in that prevalence estimates may be influenced by the year of study relative to these mini-cohorts.
spellingShingle Ebmeier, K
Mutch, W
Calder, SA
Crawford, JR
Stewart, L
Besson, J
Does idiopathic parkinsonism in Aberdeen follow intrauterine influenza?
title Does idiopathic parkinsonism in Aberdeen follow intrauterine influenza?
title_full Does idiopathic parkinsonism in Aberdeen follow intrauterine influenza?
title_fullStr Does idiopathic parkinsonism in Aberdeen follow intrauterine influenza?
title_full_unstemmed Does idiopathic parkinsonism in Aberdeen follow intrauterine influenza?
title_short Does idiopathic parkinsonism in Aberdeen follow intrauterine influenza?
title_sort does idiopathic parkinsonism in aberdeen follow intrauterine influenza
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AT stewartl doesidiopathicparkinsonisminaberdeenfollowintrauterineinfluenza
AT bessonj doesidiopathicparkinsonisminaberdeenfollowintrauterineinfluenza