Atomic snapshots of an RNA packaging motor reveal conformational changes linking ATP hydrolysis to RNA translocation.
Many viruses package their genome into preformed capsids using packaging motors powered by the hydrolysis of ATP. The hexameric ATPase P4 of dsRNA bacteriophage phi12, located at the vertices of the icosahedral capsid, is such a packaging motor. We have captured crystallographic structures of P4 for...
Prif Awduron: | Mancini, E, Kainov, D, Grimes, J, Tuma, R, Bamford, D, Stuart, D |
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Fformat: | Journal article |
Iaith: | English |
Cyhoeddwyd: |
2004
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Eitemau Tebyg
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Mechanism of RNA packaging motor.
gan: Mancini, E, et al.
Cyhoeddwyd: (2012) -
Hexameric molecular motors: P4 packaging ATPase unravels the mechanism.
gan: Kainov, D, et al.
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Production, crystallization and preliminary X-ray crystallographic studies of the bacteriophage phi 12 packaging motor.
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Order and disorder in crystals of hexameric NTPases from dsRNA bacteriophages.
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Structural basis of mechanochemical coupling in a hexameric molecular motor.
gan: Kainov, D, et al.
Cyhoeddwyd: (2008)