Molecular characterization of a novel geranylgeranyl pyrophosphate synthase from Plasmodium parasites.

Molecular characterization of a novel geranylgeranyl pyrophosphate synthase from Plasmodium parasites.

We present here a study of a eukaryotic trans-prenylsynthase from the malaria pathogen Plasmodium vivax. Based on the results of biochemical assays and contrary to previous indications, this enzyme catalyzes the production of geranylgeranyl pyrophosphate (GGPP) rather than farnesyl pyrophosphate (FP...

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Bibliographic Details
Main Authors:	Artz, J, Wernimont, A, Dunford, J, Schapira, M, Dong, A, Zhao, Y, Lew, J, Russell, R, Ebetino, F, Oppermann, U, Hui, R
Format:	Journal article
Language:	English
Published:	2011

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