Quantitative prediction of NF-kappa B DNA-protein interactions.
We describe a general method based on principal coordinates analysis to predict the effects of single-nucleotide polymorphisms within regulatory sequences on DNA-protein interactions. We use binding data for the transcription factor NF-kappaB as a test system. The method incorporates the effects of...
Κύριοι συγγραφείς: | , , , |
---|---|
Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
2002
|