Quantitative prediction of NF-kappa B DNA-protein interactions.

Quantitative prediction of NF-kappa B DNA-protein interactions.

We describe a general method based on principal coordinates analysis to predict the effects of single-nucleotide polymorphisms within regulatory sequences on DNA-protein interactions. We use binding data for the transcription factor NF-kappaB as a test system. The method incorporates the effects of...

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Bibliographische Detailangaben
Hauptverfasser:	Udalova, I, Mott, R, Field, D, Kwiatkowski, D
Format:	Journal article
Sprache:	English
Veröffentlicht:	2002

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