Quantitative prediction of NF-kappa B DNA-protein interactions.
We describe a general method based on principal coordinates analysis to predict the effects of single-nucleotide polymorphisms within regulatory sequences on DNA-protein interactions. We use binding data for the transcription factor NF-kappaB as a test system. The method incorporates the effects of...
मुख्य लेखकों: | Udalova, I, Mott, R, Field, D, Kwiatkowski, D |
---|---|
स्वरूप: | Journal article |
भाषा: | English |
प्रकाशित: |
2002
|
समान संसाधन
-
Comparing the fine specificity of DNA binding by NF-kappaB p50 and p52 using principal coordinates analysis.
द्वारा: Nijnik, A, और अन्य
प्रकाशित: (2003) -
Interaction of AP-1 with a cluster of NF-kappa B binding elements in the human TNF promoter region.
द्वारा: Udalova, I, और अन्य
प्रकाशित: (2001) -
Complex NF-kappaB interactions at the distal tumor necrosis factor promoter region in human monocytes.
द्वारा: Udalova, I, और अन्य
प्रकाशित: (1998) -
Direct evidence for involvement of NF-kappaB in transcriptional activation of tumor necrosis factor by a spirochetal lipoprotein.
द्वारा: Udalova, I, और अन्य
प्रकाशित: (2000) -
Association of accelerated erosive rheumatoid arthritis with a polymorphism that alters NF-kappaB binding to the TNF promoter region.
द्वारा: Udalova, I, और अन्य
प्रकाशित: (2002)