Trappin-2 promotes early clearance of Pseudomonas aeruginosa through CD14-dependent macrophage activation and neutrophil recruitment
Microaspiration of Pseudomonas aeruginosa contributes to the pathogenesis of nosocomial pneumonia. Trappin-2 is a host defense peptide that assists with the clearance of P. aeruginosa through undefined mechanisms. A model of macrophage interactions with replicating P. aeruginosa (strain PA01) in ser...
Main Authors: | Wilkinson, T, Dhaliwal, K, Hamilton, T, Lipka, A, Farrell, L, Davidson, D, Duffin, R, Morris, A, Haslett, C, Govan, J, Gregory, C, Sallenave, J, Simpson, A |
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Format: | Journal article |
Published: |
Elsevier
2010
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