Trappin-2 promotes early clearance of Pseudomonas aeruginosa through CD14-dependent macrophage activation and neutrophil recruitment

Microaspiration of Pseudomonas aeruginosa contributes to the pathogenesis of nosocomial pneumonia. Trappin-2 is a host defense peptide that assists with the clearance of P. aeruginosa through undefined mechanisms. A model of macrophage interactions with replicating P. aeruginosa (strain PA01) in ser...

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Bibliographic Details
Main Authors: Wilkinson, T, Dhaliwal, K, Hamilton, T, Lipka, A, Farrell, L, Davidson, D, Duffin, R, Morris, A, Haslett, C, Govan, J, Gregory, C, Sallenave, J, Simpson, A
Format: Journal article
Published: Elsevier 2010

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