Compression of a pressurized spherical shell by a spherical or flat probe
Measuring the mechanical properties of cells and tissues often involves indentation with a sphere or compression between two plates. Different theoretical approaches have been developed to retrieve material parameters (e.g., elastic modulus) or state variables (e.g., pressure) from such experiments....
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
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Springer
2022
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| _version_ | 1826309252311941120 |
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| author | Couturier, E Vella, D Boudaoud, A |
| author_facet | Couturier, E Vella, D Boudaoud, A |
| author_sort | Couturier, E |
| collection | OXFORD |
| description | Measuring the mechanical properties of cells and tissues often involves indentation with a sphere or compression between two plates. Different theoretical approaches have been developed to retrieve material parameters (e.g., elastic modulus) or state variables (e.g., pressure) from such experiments. Here, we extend previous theoretical work on indentation of a spherical pressurized shell by a point force to cover indentation by a spherical probe or a plate. We provide formulae that enable the modulus or pressure to be deduced from experimental results with realistic contact geometries, giving different results that are applicable depending on pressure level. We expect our results to be broadly useful when investigating biomechanics or mechanobiology of cells and tissues.
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| first_indexed | 2024-03-07T07:32:54Z |
| format | Journal article |
| id | oxford-uuid:18a85b84-49f8-48fe-8da5-771e81f9aab3 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T07:32:54Z |
| publishDate | 2022 |
| publisher | Springer |
| record_format | dspace |
| spelling | oxford-uuid:18a85b84-49f8-48fe-8da5-771e81f9aab32023-02-14T12:22:41ZCompression of a pressurized spherical shell by a spherical or flat probeJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:18a85b84-49f8-48fe-8da5-771e81f9aab3EnglishSymplectic ElementsSpringer2022Couturier, EVella, DBoudaoud, AMeasuring the mechanical properties of cells and tissues often involves indentation with a sphere or compression between two plates. Different theoretical approaches have been developed to retrieve material parameters (e.g., elastic modulus) or state variables (e.g., pressure) from such experiments. Here, we extend previous theoretical work on indentation of a spherical pressurized shell by a point force to cover indentation by a spherical probe or a plate. We provide formulae that enable the modulus or pressure to be deduced from experimental results with realistic contact geometries, giving different results that are applicable depending on pressure level. We expect our results to be broadly useful when investigating biomechanics or mechanobiology of cells and tissues. |
| spellingShingle | Couturier, E Vella, D Boudaoud, A Compression of a pressurized spherical shell by a spherical or flat probe |
| title | Compression of a pressurized spherical shell by a spherical or flat probe |
| title_full | Compression of a pressurized spherical shell by a spherical or flat probe |
| title_fullStr | Compression of a pressurized spherical shell by a spherical or flat probe |
| title_full_unstemmed | Compression of a pressurized spherical shell by a spherical or flat probe |
| title_short | Compression of a pressurized spherical shell by a spherical or flat probe |
| title_sort | compression of a pressurized spherical shell by a spherical or flat probe |
| work_keys_str_mv | AT couturiere compressionofapressurizedsphericalshellbyasphericalorflatprobe AT vellad compressionofapressurizedsphericalshellbyasphericalorflatprobe AT boudaouda compressionofapressurizedsphericalshellbyasphericalorflatprobe |