Introducing the ESAT-6 free IGRA, a companion diagnostic for TB vaccines based on ESAT-6.

Introducing the ESAT-6 free IGRA, a companion diagnostic for TB vaccines based on ESAT-6.

There is a need for an improved vaccine for tuberculosis. ESAT-6 is a cardinal vaccine antigen with unique properties and is included in several vaccine candidates in development. ESAT-6 is also the core antigen in the IFN-γ release assays (IGRA) used to diagnose latent infection, rendering IGRA tes...

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Bibliographic Details
Main Authors:	Ruhwald, M, de Thurah, L, Kuchaka, D, Zaher, MR, Salman, AM, Abdel-Ghaffar, A-R, Shoukry, FA, Michelsen, SW, Soborg, B, Blauenfeldt, T, Mpagama, S, Hoff, ST, Agger, EM, Rosenkrands, I, Aagard, C, Kibiki, G, El-Sheikh, N, Andersen, P
Format:	Journal article
Language:	English
Published:	Nature Publishing Group 2017

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