Mechanism of intramembrane proteolysis investigated with purified rhomboid proteases.

Mechanism of intramembrane proteolysis investigated with purified rhomboid proteases.

Intramembrane proteases have the unusual property of cleaving peptide bonds within the lipid bilayer, an environment not obviously suited to a water-requiring hydrolysis reaction. These enzymes include site-2 protease, gamma-secretase/presenilin, signal peptide peptidase and the rhomboids, and they...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Lemberg, M, Menendez, J, Misik, A, Garcia, M, Koth, C, Freeman, M
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2005

Eitemau Tebyg

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