Mechanism of intramembrane proteolysis investigated with purified rhomboid proteases.

Mechanism of intramembrane proteolysis investigated with purified rhomboid proteases.

Intramembrane proteases have the unusual property of cleaving peptide bonds within the lipid bilayer, an environment not obviously suited to a water-requiring hydrolysis reaction. These enzymes include site-2 protease, gamma-secretase/presenilin, signal peptide peptidase and the rhomboids, and they...

書目詳細資料
Main Authors:	Lemberg, M, Menendez, J, Misik, A, Garcia, M, Koth, C, Freeman, M
格式:	Journal article
語言:	English
出版:	2005

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