Mechanism of intramembrane proteolysis investigated with purified rhomboid proteases.

Intramembrane proteases have the unusual property of cleaving peptide bonds within the lipid bilayer, an environment not obviously suited to a water-requiring hydrolysis reaction. These enzymes include site-2 protease, gamma-secretase/presenilin, signal peptide peptidase and the rhomboids, and they...

詳細記述

書誌詳細
主要な著者: Lemberg, M, Menendez, J, Misik, A, Garcia, M, Koth, C, Freeman, M
フォーマット: Journal article
言語:English
出版事項: 2005