PIP(2)-binding site in Kir channels: definition by multiscale biomolecular simulations.

PIP(2)-binding site in Kir channels: definition by multiscale biomolecular simulations.

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Phosphatidylinositol bisphosphate (PIP(2)) is an activator of mammalian inwardly rectifying potassium (Kir) channels. Multiscale simulations, via a sequential combination of coarse-grained and atomistic molecular dynamics, enabled exploration of the interactions of PIP(2) molecules within the inner...

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Bibliographic Details
Main Authors:	Stansfeld, P, Hopkinson, R, Ashcroft, F, Sansom, MS
Format:	Journal article
Language:	English
Published:	2009

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