A low-frequency inactivating Akt2 variant enriched in the Finnish population is associated with fasting insulin levels and Type 2 Diabetes risk.

A low-frequency inactivating Akt2 variant enriched in the Finnish population is associated with fasting insulin levels and Type 2 Diabetes risk.

To identify novel coding association signals and facilitate characterization of mechanisms influencing glycemic traits and type 2 diabetes risk, we analyzed 109,215 variants derived from exome array genotyping together with an additional 390,225 variants from exome sequence in up to 39,339 normoglyc...

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Bibliographic Details
Main Authors: Manning, A, Highland, H, Gasser, J, Mahajan, A, Chen, Y, Pearson, R, McVean, G, Robertson, N, Rayner, N, van de Bunt, G, Groves, C, Neville, M, Blancher, C, Buck, G, Buck, D, Trakalo, J, Owen, K, Levy, J, Karpe, F, Farmer, A, Donnelly, P, McCarthy, M, Gloyn, A, Lindgren, C
Format: Journal article
Language:English
Published: American Diabetes Association 2017

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