Utrophin binds laterally along actin filaments and can couple costameric actin with sarcolemma when overexpressed in dystrophin-deficient muscle.

Utrophin binds laterally along actin filaments and can couple costameric actin with sarcolemma when overexpressed in dystrophin-deficient muscle.

Dystrophin is widely thought to mechanically link the cortical cytoskeleton with the muscle sarcolemma. Although the dystrophin homolog utrophin can functionally compensate for dystrophin in mice, recent studies question whether utrophin can bind laterally along actin filaments and anchor filaments...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính:	Rybakova, I, Patel, JR, Davies, K, Yurchenco, P, Ervasti, J
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	2002

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