Virus-specific CD8+ T lymphocytes within the normal human liver.

Virus-specific CD8+ T lymphocytes within the normal human liver.

The frequency and phenotype of human antiviral memory CD8(+) T cells in blood are well studied, yet little is known about their distribution within tissues. Analysis of antiviral CD8(+) T cell populations derived from a unique set of normal liver and blood samples identified a consistent population...

Full description

Bibliographic Details
Main Authors:	Ward, S, Jonsson, JR, Sierro, S, Clouston, A, Lucas, M, Vargas, A, Powell, E, Klenerman, P
Format:	Journal article
Language:	English
Published:	2004

Similar Items

CD4+CD25+T-regulatory lymphocytes control expansion of hepatitis virus specific CD8+T cells.
by: Rushbrook, S, et al.
Published: (2003)

Ex vivo analysis of phenotype and TCR usage in relation to CD45 isoform expression on cytomegalovirus-specific CD8+ T lymphocytes.
by: Vargas, A, et al.
Published: (2001)

Regulatory T cells suppress in vitro proliferation of virus-specific CD8+ T cells during persistent hepatitis C virus infection.
by: Rushbrook, S, et al.
Published: (2005)

Regulatory T cells suppress in vitro proliferation of virus-specific CD8(+) T cells during persistent hepatitis C virus infection
by: Rushbrook, S, et al.
Published: (2005)

Immunosuppression for liver transplantation with tacrolimus impairs specific cytomegalovirus CD8 immune responses
by: Hassan-Walker, A, et al.
Published: (2000)

CD8+ cytotoxic lymphocyte responses against cytomegalovirus after liver transplantation: correlation with time from transplant to receipt of tacrolimus.
by: Hassan-Walker, A, et al.
Published: (2001)

Functional discrepancies in HIV-specific CD8+ T-lymphocyte populations are related to plasma virus load.
by: Oxenius, A, et al.
Published: (2002)

Do antiviral CD8+ T cells select hepatitis C virus escape mutants? Analysis in diverse epitopes targeted by human intrahepatic CD8+ T lymphocytes.
by: Komatsu, H, et al.
Published: (2006)

Underwhelming the immune response: effect of slow virus growth on CD8+-T-lymphocyte responses.
by: Bocharov, G, et al.
Published: (2004)

Underwhelming the immune response: Effect of slow virus growth on CD(8+) T-lymphocyte responses
by: Bocharov, G, et al.
Published: (2004)

Skewed maturation of memory HIV-specific CD8 T lymphocytes.
by: Champagne, P, et al.
Published: (2001)

Skewed maturation of memory HIV-specific CD8 T lymphocytes.
by: Champagne, P, et al.
Published: (2001)

Sustained dysfunction of antiviral CD8+ T lymphocytes after infection with hepatitis C virus.
by: Gruener, N, et al.
Published: (2001)

CD8+ lymphocyte (CD8+L) responses in acute hepatitis C virus (HCV) infection
by: Christie, J, et al.
Published: (1998)

The role of virus-specific CD8+cells in liver damage and viral control during persistent hepatitis B virus infection
by: Maini, M, et al.
Published: (2000)

The role of virus-specific CD8(+) cells in liver damage and viral control during persistent hepatitis B virus infection.
by: Maini, M, et al.
Published: (2000)

Evolution of diverse antiviral CD8+ T cell populations after murine cytomegalovirus infection.
by: Sierro, S, et al.
Published: (2005)

CD8+ T lymphocyte responses are induced during acute hepatitis C virus infection but are not sustained.
by: Lechner, F, et al.
Published: (2000)

CD8(+) T lymphocyte (CD8(+)L) responses in acute and chronic hepatitis C virus (HCV) infection.
by: Christie, J, et al.
Published: (1998)

Virus-specific CD4+ T cell responses in chronic HCV infection in blood and liver identified by antigen-specific upregulation of CD154.
by: Mueller, M, et al.
Published: (2010)

The magnitude and kinetics of the mucosal HIV-specific CD8+ T lymphocyte response and virus RNA load in breast milk.
by: Mahlokozera, T, et al.
Published: (2011)

The magnitude and kinetics of the mucosal HIV-specific CD8+ T lymphocyte response and virus RNA load in breast milk
by: Mahlokozera, T, et al.
Published: (2011)

Properties of murine (CD8+)CD27- T cells.
by: Baars, P, et al.
Published: (2005)

Pervasive influence of hepatitis C virus on the phenotype of antiviral CD8+ T cells.
by: Lucas, M, et al.
Published: (2004)

Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection.
by: Borrow, P, et al.
Published: (1994)

Differential B7-CD28 costimulatory requirements for stable and inflationary mouse cytomegalovirus-specific memory CD8 T cell populations.
by: Arens, R, et al.
Published: (2011)

Large scale analysis of pediatric antiviral CD8+ T cell populations reveals sustained, functional and mature responses.
by: Komatsu, H, et al.
Published: (2006)

Gamma Delta T-lymphocytes in Hepatitis C and Chronic Liver Disease.
by: Rajoriya, N, et al.
Published: (2014)

CD161 expression on hepatitis C virus-specific CD8+ T cells suggests a distinct pathway of T cell differentiation.
by: Northfield, J, et al.
Published: (2008)

Ex vivo phenotype and frequency of influenza virus-specific CD4 memory T cells.
by: Lucas, M, et al.
Published: (2004)

Quantitative ex vivo analysis of functional virus-specific CD8 T lymphocytes in the blood and genital tract of HIV-infected women.
by: Kaul, R, et al.
Published: (2003)

Epitope specificity and relative clonal abundance do not affect CD8 differentiation patterns during lymphocytic choriomeningitis virus infection.
by: Munitic, I, et al.
Published: (2009)

CD8 independence and specificity of cytotoxic T lymphocytes restricted by HLA-Aw68.1.
by: Cerundolo, V, et al.
Published: (1991)

Human cytolytic and interferon gamma-secreting CD8+ T lymphocytes specific for Mycobacterium tuberculosis.
by: Lalvani, A, et al.
Published: (1998)

Comprehensive analysis of CD8(+)-T-cell responses against hepatitis C virus reveals multiple unpredicted specificities.
by: Lauer, G, et al.
Published: (2002)

Studies of human antiviral CD8+ lymphocytes using class I peptide tetramers.
by: Lechner, F, et al.
Published: (2001)

Defining the directionality and quality of influenza virus-specific CD8+ T cell cross-reactivity in individuals infected with hepatitis C virus.
by: Kasprowicz, V, et al.
Published: (2008)

Polyfunctional cytomegalovirus-specific CD4+ and pp65 CD8+ T cells protect against high-level replication after liver transplantation.
by: Nebbia, G, et al.
Published: (2008)

Prolonged activation of virus-specific CD8+T cells after acute B19 infection.
by: Isa, A, et al.
Published: (2005)

HIV-1-specific CD4+ T lymphocyte turnover and activation increase upon viral rebound.
by: Scriba, T, et al.
Published: (2005)