The role of virus-specific CD8(+) cells in liver damage and viral control during persistent hepatitis B virus infection.

The role of virus-specific CD8(+) cells in liver damage and viral control during persistent hepatitis B virus infection.

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Hepatitis B virus (HBV) is a noncytopathic virus, and the recognition of infected hepatocytes by HBV-specific CD8 cells has been assumed to be the central mechanism causing both liver damage and virus control. To understand the role of cytotoxic T cells in the pathogenesis of HBV infection, we used...

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Bibliographic Details
Main Authors: Maini, M, Boni, C, Lee, C, Larrubia, JR, Reignat, S, Ogg, G, King, A, Herberg, J, Gilson, R, Alisa, A, Williams, R, Vergani, D, Naoumov, N, Ferrari, C, Bertoletti, A
Format: Journal article
Language:English
Published: 2000

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