Unregulated smooth-muscle myosin in human intestinal neoplasia.

A recent study described a recessive ATPase activating germ-line mutation in smooth-muscle myosin (smmhc/myh11) underlying the zebrafish meltdown (mlt) phenotype. The mlt zebrafish develops intestinal abnormalities reminiscent of human Peutz-Jeghers syndrome (PJS) and juvenile polyposis (JP). To exa...

Full beskrivning

Bibliografiska uppgifter
Huvudupphovsmän:	Alhopuro, P, Phichith, D, Tuupanen, S, Sammalkorpi, H, Nybondas, M, Saharinen, J, Robinson, J, Yang, Z, Chen, L, Orntoft, T, Mecklin, J, Järvinen, H, Eng, C, Moeslein, G, Shibata, D, Houlston, R, Lucassen, A, Tomlinson, I, Launonen, V, Ristimäki, A, Arango, D, Karhu, A, Sweeney, H, Aaltonen, L
Materialtyp:	Journal article
Språk:	English
Publicerad:	2008

Unregulated smooth-muscle myosin in human intestinal neoplasia.

Liknande verk