Vimentin restrains regulatory T-cell suppression of graft-versus-host disease

Vimentin restrains regulatory T-cell suppression of graft-versus-host disease

Regulatory T-cells (Treg) are critical for maintaining immune homeostasis. However, current Treg immunotherapies do not optimally treat inflammatory diseases in patients. Understanding the cellular processes that control Treg function may allow for the augmentation of therapeutic efficacy. In contra...

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Bibliographic Details
Main Authors: McDonal-Hyman, C, Muller, J, Loschi, M, Thangavelu, G, Saha, A, Kumari, S, Reichenbach, D, Smith, M, Zhang, G, Koehn, BH, Lin, J, Mitchell, JS, Fife, BT, Panoskaltsis-Mortari, A, Feser, C, Kirchmeier, AK, Osborn, MJ, Hippen, KL, Kelekar, A, Serody, JS, Turka, LA, Munn, DH, Chi, H, Neubert, TA, Dustin, ML, Blazar, BR, Dustin, M
Format: Journal article
Published: American Society for Clinical Investigation 2018

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