Integrating genome-wide polygenic risk scores and non-genetic risk to predict colorectal cancer diagnosis using UK Biobank data: population based cohort study
<p><strong>Objective:</strong> To evaluate the benefit of combining polygenic risk scores with the QCancer-10 (colorectal cancer) prediction model for non-genetic risk to identify people at highest risk of colorectal cancer.</p> <p><strong>Design:</str...
Main Authors: | Briggs, SEW, Law, P, East, JE, Wordsworth, S, Dunlop, M, Houlston, R, Tomlinson, I, Hippisley-Cox, J |
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Format: | Journal article |
Language: | English |
Published: |
BMJ Publishing Group
2022
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